"全滅" appears in a manga in speech by a schoolteacher noting that some of his pupils (all the members of the school baseball club in his class) are fast asleep. Is it the same sort of exaggeration as the English phrase "totally wasted", i.e. he is being somewhat sarcastic? Here's the original complete sentence "今日も野球部は全滅なのか?" He's teaching Japanese history, if that helps.