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An anti-vaxxer is a person who is against vaccinations, either for him/her/themselves, or against any law or rule requiring them (as for attendance at a school). This term has become used especially often with the covid-19 vaccines, and in the United States it has also become something of a political issue.

The large number of anti-vaxxers can potentially endanger the population as a whole.

It appears in the Merriam-Webster dictionary.
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