Oh of course you have to use commas - and their placing can make a big difference. I'm not saying ignore them completely. But use them as you see fit. There are strict rules in, say, German - you must use a comma before dass regardless of how you pronounce it or what it means. In English, fit them to your meaning. Use it if it helps shape the meaning, or if it helps guide the pronunciation. There are some conventions (e.g. 'a tall, dark stranger': two equal adjectives before a noun), but you can ignore them if they don't fit what you want to say or how you say it.