crossbridge cycling

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Impaired Ca2+ release from sarcolemma and sarcoplasmic reticulum, inhibition of crossbridge cycling,... also contribute to systolic dysfunction.

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Main Entry: cross·bridge
Pronunciation: 'kros-"brij
Function: noun
: the globular head of a myosin molecule that projects from a myosin filament in muscle and in the sliding filament hypothesis of muscle contraction is held to attach temporarily to an adjacent actin filament and draw it into the A band of a sarcomere between the myosin filaments
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
 
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