This is the whole sentence:Please give us the complete sentence, and a bit more context.
Great explanation !This is talking about a hotel chain (a set of hotels owned and run by the same company). Their "brand" is their famous name.
Some of the hotels are located at "common travel destinations": places that tourists visit. Using the "destination-inspired design" idea, each of those hotels will have a design that matches the "destination" where it is located, instead of all the hotels having the same design (because they are part of a chain).
So if one hotel (in the chain) is in London, and one is on a beach in Honolulu, the London one will have a sophisticated urban design and decorations, while the Honolulu one will have a casual tropical theme.